The leaf you were holding with the large brown area needs attention. Cut it off an inch or two below the discoloration. Could be pythium bacteria (soft brown rot), so wash your hands and the cutting utensil afterwards. Actually, use alcohol and or a flame to sterilize the utensil before and afterwards. I'd then sprinkle cinnamon on the end of the cut to ward off infection.
Water getting on the leaves, cool temps near the window, and too low of air flow increase the spotting. Especially with the pythium.
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